researchBackground of

• 01At a certain point, for patients who have repeated exacerbations of heart failure after unsuccessful drug therapy, heart transplantation is the only treatment option left.
• 02However, only a limited number of patients can actually undergo heart transplantation, and in many cases an assisted artificial heart is used during the waiting period, but it is associated with complications such as blood clots and infection.
• 03It is desirable to develop alternative/combination therapies other than drugs that are effective in reducing cardiac dilatation and the progression of heart failure, and that can be widely applied.
• 04The development of medical devices for alternative and combination therapies has been conducted in the U.S. and Europe to date, but none have been put into practical use.
• 05The iCorNet Institute has focused on cardiac remodeling as the root cause of heart failure exacerbations, and has been researching and developing therapeutic tools that effectively suppress remodeling itself.
  Although it is known from previous studies that the method of wrapping the heart with a net has a certain effect, it has also been found that the method of simply compressing the ventricular area with equal force impairs the diastolic function of the right ventricle and does not improve heart failure.

テーラーメイド方式心臓形状矯正ネット
solves these problems.
newTreatment of Dilated Cardiomyopathy

personalized system
Heart Shape Correction NetOverview and Features

• 013D heart modeling from patient heart images
• 02Creation of computerized knitting machine patterns from 3D heart models
• 03心臓形状矯正ネット装着時の心機能・エネルギー効率をシミュレーション技術を用いて予測し、ネット形状と物性が最適化する設計
  →Corresponds to diurnal variation in circulating blood volume
  →Able to determine patient suitability and predict postoperative cardiac function
• 04 A computer-controlled, seamless knitting machine knits 3D shaped nets without sewing.
  →あらかじめ患者の心臓画像データを元に心臓形状矯正ネットを編むことで術中の調整が不要。
  →Minimally invasive (shorter surgery time, small incision approach)
• 05Avoids right ventricular dilatation defects
  →Sufficient compression setting for left ventricle
  →Certain prevention of cardiac remodeling

Tested Products and Developed TechnologiesOverview of

3D heart
Model Creation

Heart shape data and
Fusion of pressure data

Thread count adjustment (net physical properties database)

Thus, each patient's
To match individual image data
To create a tailor-made net,
After the image data is provided.
It takes about one month to complete.